Irivist eyes is a supplement in soft capsules indicated to improve visual quality and provide protection for tired eyes. The formulation combines vitamins (E, A, B1 and B2) and minerals (Zinc) that support normal visual function, with Blueberry, a fruit rich in antioxidants, vitamins (especially A and C), mineral salts (potassium and phosphorus) and anthocyanins. In particular, the latter improve the adaptation of sight in the dark, increasing the speed of regeneration of retinal purpura, a red pigment contained in the retina that favors vision in the dark. These blue fruits also promote the functionality of the venous microcirculation, reinforcing the capillaries.
In the formulation of Irivist Taurine is also present, able to counteract the aging process thanks to its anti-free radical action. This amino acid is also important for the synthesis of nitric oxide (NO), a powerful vasodilator agent. In the aesthetic field, taurine is used to restore strength and vitality to the hair. Furthermore, it would seem to be useful in case of macular degeneration. Taurine has long been implicated in the protection of the retina from retinal degenerative diseases, but the underlying molecular mechanisms remain unclear. Retinal neurodegeneration is an early event in the pathogenesis of diabetic retinopathy (DR) that precedes and participates in the microcirculatory abnormalities that occur in DR. According to some studies, in fact, taurine could protect retinal cells from diabetic attacks, reducing retinal reactive gliosis, improving retinal synaptic connections and decreasing retinal cell apoptosis.
In addition to these substances, Irivist eyes also contains reduced glutathione, lutein and carotenoids, all substances that support and protect the visual function, helping the eyes to sustain more stressful conditions.
Nutrients (mg)
* Note Values calculated on a single administration
-Endothelin-1 (ET-1), a powerful vasoconstrictor, is involved in the vascular alteration of the retina and in oxidative stress in glaucomatous eyes. Taurine (TAU), a naturally occurring amino acid, is known for its neuroprotective and antioxidant properties. In this study, its neuroprotective properties are assessed with respect to the retinal and optical nerve damage induced by ET-1.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6183037/
What we have seen is that retinal oxidative stress has been reduced in all groups treated with TAU, particularly in the pre-treatment group. The results suggest that treatment with TAU, in particular pre-treatment, prevents retinal and apoptotic cells induced by ET-1 and therefore prevents changes in retinal and optic nerve morphology. The protective effect of TAU against ET-1-induced retino and optic nerve damage is associated with a reduction in retinal oxidative stress.
-Retinal neurodegeneration is an early event in the pathogenesis of diabetic retinopathy (DR). The objective of this study was to investigate the role and mechanisms of taurine in the diabetic retina. What has been found is that taurine has prevented retinal cell and ganglion cell loss and maintained the balance of the Bcl-2 / Bax ratio in diabetic rats. Taurine also prevented upregulation of the fibrillar acidic protein glia (GFAP) and reduced retinal reactive gliosis. Furthermore, taurine reduced plasma glutamate and tyrosine levels, which were elevated in diabetic rats. In conclusion, taurine can protect retinal cells from diabetic attacks by activating Tau-T, reducing retinal reactive gliosis, improving retinal synaptic connections and decreasing retinal cell apoptosis. Therefore, treatment with taurine may be a new approach for early diabetic retinopathies.
