Muscle cells need a large number of substances (including magnesium) to allow proteins to interact and develop an organized contraction within them. The lack of even one of these elements can irritate the muscle and develop a contracture. The contracture may partially or completely involve the muscle and, in some cases, also affects the adjacent muscles. Preserving as much as possible the proper functioning of the nervous system and contributing to good muscle function is important, also through food integration.
Magnesium, a mineral that contributes to normal muscle and psychological function, as it is involved in muscle contraction and nerve conduction at the central and peripheral levels. In periods of greater tension, our organism uses more magnesium reserves; therefore, it is important to keep its quantity in the body at proper levels. A deficiency, which also contributes to stress, often causes tension and cramps with real muscular pain (myalgias). The chelated form of magnesium is responsible for its greater absorption.
Boswellia serrata (titrated to 30% in AKBA-boswellic acids), tree from whose bark the scented oil-rubber resin is extracted, composed of a mixture of boswellic acids (triterpene compounds). These are able to counteract localized states of tension, having anti-inflammatory properties.
L-tryptophan, an essential amino acid that our body can not synthesize and, therefore, must be introduced with the diet. It is the precursor of serotonin, one of the main neurotransmitters responsible for mood, but also melatonin, the regulating hormone of the sleep-wake cycle.
* Note Values calculated on a single administration
Since ancient times the analgesic and anti-inflammatory properties of the dried Boswellia serrata gum is known. Studies conducted on animal models have shown that boswellic acids are able to reduce not only the infiltration and migration of polymorphonuclear leukocytes, but also the biosynthesis of leukotrienes. Studies conducted by the researcher Cuaz-Pérolin have shown that a particular boswellic acid, the acetyl-11-keto boswellic acid (AKBA), contained in the extract, behaves as a natural inhibitor of the transcription of NFkB (one of the main mediators inflammatory).
Below is the link of one of the articles that highlights the promising effects of this compound:
https://www.ncbi.nlm.nih.gov/pubmed/?term=Anti-inflammatory+and+anti-atherogenic+effects+of+the+NF-kappaB+inhibitor+acetyl-11-keto-beta-boswellic acid + + in + LPS
Another experimental study supports the potential of Boswellia serrata (BSE) extracts for the treatment of various inflammatory diseases.
The purpose of this study, in particular, was to evaluate the safety and efficacy of a new form of release of Boswellia serrata to counter osteo-muscular pain.
52 young young rugby players were recruited with acute knee pain and inflammation. Informed participants have freely decided to follow a standard management to control joint pain. Parameters associated with pain and musculoskeletal inflammation and measurements of health and joint function were evaluated after a 4-week supplementation.
A significant beneficial effect was observed for all the evaluated parameters, namely: local stress pain; walkable distance without pain (treadmill test); minimum joint payment; structural damage (joints, tendons, muscles) and intramuscular hematomas.