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  • Neurofast 30 compresse

Neurofast 30 compresse

PharmExtracta S.r.l.

€16,90 €14,36

In stock

Neurofast multilayer tablets with differentiated release contain Valeroselect® based on:

- Valeriana officinalis extract standardized and titrated to 0.8% in fast-release valerenic acids (fast release);

- Crataegus spp. Extract (Hawthorn) standardized and titrated to 1.8% in vitexin-2-ramonoside in normal release form (normal release);

- Standardized Passiflora incarnata extract and titrated at 3.5% in slow-release total flavonoids (slow release).

Valeriana officinalis is a flowering plant used mainly as a natural sedative. All valerian species contain:

- Essential oils (esters of valerianic acid, valerenic acid, caryophyllene, terpinolene, valerenol, valerenal and diterpene compounds known as iridoids);

-Alkaloids (valerine, actinidine, catinin and alpha-pyrrchetone);

-Flavonoids (linarin, 6-methylapigenin and hesperidin).

The root of the plant is used which has sedative and calming properties, favoring sleep.

The mechanism of action of its constituents is quite well known. The esters of valerianic acids and iridoids inhibit the enzyme GABA transaminase (GABA T), responsible for the metabolic degradation of the neurotransmitter gamma-amino butyric acid (GABA). This chemical mediator is notoriously associated with inhibitory neuronal phenomena and is also responsible for the induction of sleep in humans.

More recent studies have shown that even some of the alkaloids can have a more or less direct influence on the metabolism of GABA, but their mechanism is still unclear. Finally, it seems that some of the terpenes and flavonoids can act as agonists of Adenosine receptors (those inhibited by caffeine) and be partly responsible for the hypno-inducing action, spasmolytic in the intestinal and reducing blood pressure.

The flowers and leaves of Hawthorn contain, among the various chemical compounds, flavonols, proanthocyanidins and flavones, including vitexin, which give this plant an effective activity on the heart muscle. In fact, these substances cause vasodilation, particularly in the coronary districts, with an increase in blood flow; at the same time they decrease blood pressure and reduce the heart rate significantly. One of the properties of hawthorn is the sedative at the central level; its administration causes sedation and enhances barbiturate-induced sleep, although the mechanism of action involved in this process is not yet clear; it is very useful in very nervous patients, in whom it reduces emotion, tension and improves sleep, better if associated with plant species such as valerian (Valeriana officinalis L.) and passionflower (Passiflora incarnata L.) which complete it and enhance the sedative and anxiolytic effect. Another very interesting feature of this vegetable drug is that it is a good antioxidant. In fact, it promotes the elimination of free radicals by greatly reducing the oxidation of LDL, the particles of the so-called "bad cholesterol", which once oxidized tend to deposit in the blood vessel wall, causing the formation of atherosclerotic plaques. The use of extracts of hawthorn strongly decreases this phenomenon thus carrying out a cardioprotective activity.

The leaves and aerial parts of the Passiflora contain alkaloids, flavonoids, phytosterols, phenols, coumarins. Flavonoids have an effect on the central nervous system, especially in the area of ​​the spinal cord, used to control movements and sleep centers. Recently it has been shown that these active ingredients are able to bind to the benzodiazepine receptors located in the brain, thus explaining the calming action of this plant, which makes it one of the most widely used phytotherapics in disorders of the nerve sphere. The properties of the plant are essentially sedative and anxiolytic, and make the plant an extremely effective remedy in fighting insomnia, because they stimulate a physiological sleep without nocturnal awakenings, without producing a sense of morning numbness, and narcotic effects or addiction; this plant is useful in cases of stress, anxiety and a sense of anxiety; in the forms of hysterical, phobic, obsessive and post-traumatic neurosis, in menopausal disorders, such as nervousness, irritability, depression, tachycardia, dyspnea, hot flushes, and is preventive for heart attacks.

Nutrients (mg)

* Note Values calculated on a single administration

  • Anxiety/Insomnia
  • General well-being
  • Promote sleep and relaxation
  • Psycho-physical well being

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