Fisioreve® Tens can be prescribed as an adjunct in the states of physical and mental fatigue characterized by the recurrence of contractions, cramps, fibromyalgia syndrome and headaches and in the treatment of premenstrual syndrome.
The formulation of Fisioreve® Tens promotes a rapid recovery of well-being and physical and mental energy thanks to the high bioavailability and synergistic action of its main components.
Fisioreve Tens sachets contain Tryptophan, Magnesium, Niacin, Vitamin D, Vitamin B2 and Melatonin.
Tryptophan is an essential amino acid, ie it is not produced in an endogenous way and consequently must necessarily be introduced with the diet. It represents only 1% of the amino acids taken on average, so its concentration can often be deficient in the blood. It is the only precursor for the endogenous synthesis of serotonin, a chemical mediator that regulates the mood, and subsequently melatonin, a hormone produced by the pineal gland, whose activity is fundamental in various phases of sleep, especially during the REM phases ( Rapid Eyes Movement). In some individuals there may be low levels of these two metabolites resulting from reduced intake of L-tryptophan.
Fisioreve® Tens provides a high dose of bioavailable magnesium without any gastroenteric side effects (eg diarrhea or gastric heaviness) due to the particular formulation of the mineral salt which is supplied in chelated form.
Magnesium plays a fundamental role during the muscle decontraction phase: an excessive and prolonged contraction can give rise to phenomena such as nocturnal cramps, contractures and muscle fatigue in general.
Vitamin D and Magnesium contribute to the maintenance of normal muscle function.
Magnesium, Niacin and Vitamin B2 contribute to the normal functioning of the nervous system, to normal energy metabolism and to the reduction of tiredness and fatigue.
Melatonin is a hormone essential for its activity during sleep, especially during the REM phases or those that characterize the dream phases. Its production takes place at the level of the pineal gland starting from the amino acid L-Tryptophan. Melatonin contributes to the reduction of the time required for sleep. The beneficial effect is obtained with the intake, just before bedtime, of 1 mg of Melatonin.
Nutrients (mg)
* Note Values calculated on a single administration
Several studies have been conducted to show that adverse effects (eg sleep disorders, irritability) and dysfunctions that often appear during menopause are due to decreased levels of the essential amino acid tryptophan, a precursor of Serotonin.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609529/pdf/nihms895926
It is precisely the change in the hormonal levels typical of this period that determines the reduction of Serotonin levels.